Effect of Procyanidins in Leaky Gut Repairing in IBD

Launched by UNIVERSITY OF PADOVA · Aug 26, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a product called Grape Seed Extract Ecovitis to see if it can help improve gut health in patients with Ulcerative Colitis (UC) who are in remission. Specifically, researchers want to find out if this extract can change the balance of bacteria in the gut, improve how well the gut works, and enhance the overall quality of life for people with UC.

To participate, you need to be between 18 and 75 years old and have a confirmed diagnosis of Ulcerative Colitis that is currently in remission. If you join the trial, you will take two capsules of Ecovitis each day for eight weeks and attend two clinic visits for checkups and to answer some questions. This study is currently looking for participants, so if you or someone you know fits the eligibility criteria, it may be a good opportunity to contribute to important research on gut health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of UC confirmed by clinical, endoscopic and histopathological evidence. Disease in remission phase confirmed by clinical, endoscopic and histopathological evidence.
• • Age between 18 and 75 years old
• • Ability of subject to participate fully in all aspects of this clinical trial.
• Exclusion Criteria:
• • ● Patients that have active UC, determined by clinical, endoscopic and histopathological evidences
• • Known diagnosis of CD, indeterminate colitis, ischemic colitis, radiation colitis, diverticular disease associated with colitis or microscopic colitis
• • Positive stool culture for active C. difficile
• • Pregnant women
• • Patients under antibiotic and/or probiotic treatment within 10 days prior to Visit 1.