Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters

Launched by UNIVERSITY OF SAO PAULO · Aug 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how high-intensity exercise combined with a special type of breathing (called hypoxia) and a supplement called taurine can affect people with obesity. Researchers want to see if these methods can improve how our cells use energy and how our bodies process food, which can help with overall health. They will compare the effects of exercising in normal air versus low-oxygen conditions and see how taurine affects the results compared to a placebo (a dummy treatment).

To participate, women aged 25 to 45 with a body mass index (BMI) between 30 and 35 are invited to join. It's important that participants are not currently on a diet, exercising regularly, or experiencing menopause. Throughout the trial, participants will engage in the same exercise program, and researchers will monitor their progress. This study aims to find effective ways to treat obesity, a significant health issue in Brazil, and help improve the well-being of those affected.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women
• • Age between 25 - 45 years old;
• • BMI between 30 - 35kg/m²;
• • Not be on a diet;
• • Not be on a physical activity program;
• • Not be menopaused.
• Exclusion Criteria:
• • Smokers;
• • Alcoholics;
• • Use thyroid medication;
• • Carry out nutritional monitoring or in treatment for weight loss;
• • Hypertension;
• • Metabolical syndrome;
• • Have any comorbidity associated to obesity;
• • Drugs use.