The EEG Study Under Sevoflurane Anesthesia in Children

Launched by SECOND AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY · Aug 28, 2024

Keywords

ClinConnect Summary

This clinical trial, titled "The EEG Study Under Sevoflurane Anesthesia in Children," is investigating how general anesthesia, specifically using a drug called sevoflurane, affects the brain activity of children of different ages. Researchers are particularly interested in understanding the brain's electrical activity (measured through a test called electroencephalography or EEG) while children are under anesthesia. This study aims to learn more about how brain activity changes during anesthesia induction, maintenance, and recovery, which could help improve monitoring strategies for pediatric anesthesia in the future.

To participate in this study, children aged 1 day to 6 years old who need sevoflurane anesthesia and have a generally healthy status (rated as ASA physical status I or II) may be eligible. However, children with certain health conditions, such as severe heart or brain diseases, or those who were born prematurely, cannot participate. Parents or guardians need to give their consent for their child to take part. If eligible, participants can expect to undergo routine anesthesia procedures with additional brain monitoring to help researchers gather valuable information about how anesthesia affects young children's brains.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. aged 1 days#6 years#;
• • 2. with American Society of Anesthesiologists (ASA) physical status I or II#;
• • 3. children requiring general anesthesia under sevoflurane;
• • 4. parents or legal guardians of children who volunteered to participate in the trial; And signed the informed consent form.
• Exclusion Criteria:
• • 1. Congenital malformation or other genetic conditions that are thought to affect brain development ;
• • 2. History of severe heart, brain, liver, kidney and metabolic diseases ;
• • 3. Premature infants (≤32 weeks);
• • 4. Upper respiratory tract infection in the last two weeks.