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Search / Trial NCT06580327

Programmed Intermittent Epidural Bolus Compared With Continuous Infusion in Multiparous Women

Launched by HOLY FAMILY HOSPITAL, NAZARETH, ISRAEL · Aug 26, 2024

Trial Information

Current as of July 26, 2025

Recruiting

Keywords

Multipara Term Pregnancy Singleton Vertex Presentation Latent Phase Maternal Request For Epidural Visual Analogue Scale > 4

ClinConnect Summary

This clinical trial is studying two different methods of providing pain relief during labor for women who have given birth before (multiparous women). The researchers want to find out if a technique called programmed intermittent epidural bolus, where women receive a dose of pain relief medication every hour, is more effective at reducing sudden pain (called breakthrough pain) compared to a continuous infusion, where the same medication is given steadily over time until delivery.

To participate in the trial, women must meet specific criteria. They should be at term in their pregnancy (meaning they are close to their due date), having a single baby that is positioned head-down, and should be in the early stages of labor (with less than 6 cm of cervical dilation). They also need to request epidural pain relief and have a pain level that is significant. If you or someone you know is eligible and decides to participate, they will either receive the hourly bolus method or the continuous infusion method during labor. This trial is currently recruiting participants, and it aims to improve how pain is managed during childbirth.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. multiparous women
  • 2. Term pregnancy
  • 3. Singleton
  • 4. Vertex presentation
  • 5. Latent phase (cervical dilatation less than 6 cm)
  • 6. Epidural analgesia request
  • 7. Visual Analogue Scale score greater than 40
  • Exclusion Criteria:
  • 1. Estimated fetal weight greater than 4.0 kg
  • 2. Intra uterine fetal death
  • 3. Drug sensitivity
  • 5. Anomalous fetus 6. Contraindication for epidural analgesia

About Holy Family Hospital, Nazareth, Israel

Holy Family Hospital, located in Nazareth, Israel, is a prominent healthcare institution dedicated to providing high-quality medical services and advancing clinical research. As a clinical trial sponsor, the hospital is committed to enhancing patient care through innovative research initiatives that explore new treatments and therapies. With a focus on patient safety and ethical standards, Holy Family Hospital collaborates with healthcare professionals and researchers to contribute valuable insights to the medical community, ultimately aiming to improve health outcomes for diverse populations.

Locations

Nazareth, , Israel

Nazareth, , Israel

Patients applied

0 patients applied

Trial Officials

Raed Salim, MD

Study Chair

Holy Family Hospital, Nazareth, Israel

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported