The Effect of Aerobic and Anaerobic Exercise on Oxidative Stress and Cellular Fitness in Healthy Trained Young Men
Launched by INDONESIA UNIVERSITY · Aug 30, 2024
Trial Information
Current as of July 24, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Oxidative stress arises from an imbalance between pro-oxidant and antioxidant levels, where the pro-oxidant status, primarily reactive oxygen species (ROS), exceeds the antioxidant defense. This imbalance can damage cellular components such as membranes, lipids, proteins, DNA, and lipoproteins, leading to various chronic and degenerative diseases. The human body defends against oxidative stress through antioxidant mechanisms. Numerous studies have shown that physical exercise increases ROS production, mainly through enhanced activity of phospholipase A2 (PLA2), nicotinamide adenine dinucleo...
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Male, aged 18-23.
- • body weight of 56-70 kg and a height of 158-175 cm.
- • Systolic blood pressure values below 130 mmHg, and diastolic blood pressure below 90 mmHg.
- • maximum oxygen consumption (VO2max) is calculated to be greater than 40 mL/(kg-minute).
- Exclusion Criteria:
- • fever
- • having chronic diseases (heart disease, lung disease)
- • smoking
About Indonesia University
Indonesia University is a leading academic institution dedicated to advancing healthcare through rigorous clinical research. As a trial sponsor, the university leverages its extensive expertise in medical science and collaboration with top-tier researchers to design and implement innovative clinical trials. Committed to ethical standards and patient safety, Indonesia University aims to contribute to the global body of knowledge in medicine, enhance therapeutic options, and improve health outcomes for diverse populations. Through its comprehensive approach, the university fosters an environment of scientific inquiry and collaboration, driving progress in clinical research and education.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jakarta Pusat, Jakarta, Indonesia
Patients applied
Trial Officials
Novi Hardiany
Principal Investigator
Fakultas Kedokteran Universitas Indonesia
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported