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Search / Trial NCT06582862

The Effect of Aerobic and Anaerobic Exercise on Oxidative Stress and Cellular Fitness in Healthy Trained Young Men

Launched by INDONESIA UNIVERSITY · Aug 30, 2024

Trial Information

Current as of June 27, 2025

Enrolling by invitation

Keywords

ClinConnect Summary

Oxidative stress arises from an imbalance between pro-oxidant and antioxidant levels, where the pro-oxidant status, primarily reactive oxygen species (ROS), exceeds the antioxidant defense. This imbalance can damage cellular components such as membranes, lipids, proteins, DNA, and lipoproteins, leading to various chronic and degenerative diseases. The human body defends against oxidative stress through antioxidant mechanisms. Numerous studies have shown that physical exercise increases ROS production, mainly through enhanced activity of phospholipase A2 (PLA2), nicotinamide adenine dinucleo...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • Male, aged 18-23.
  • body weight of 56-70 kg and a height of 158-175 cm.
  • Systolic blood pressure values below 130 mmHg, and diastolic blood pressure below 90 mmHg.
  • maximum oxygen consumption (VO2max) is calculated to be greater than 40 mL/(kg-minute).
  • Exclusion Criteria:
  • fever
  • having chronic diseases (heart disease, lung disease)
  • smoking

About Indonesia University

Indonesia University is a leading academic institution dedicated to advancing healthcare through rigorous clinical research. As a trial sponsor, the university leverages its extensive expertise in medical science and collaboration with top-tier researchers to design and implement innovative clinical trials. Committed to ethical standards and patient safety, Indonesia University aims to contribute to the global body of knowledge in medicine, enhance therapeutic options, and improve health outcomes for diverse populations. Through its comprehensive approach, the university fosters an environment of scientific inquiry and collaboration, driving progress in clinical research and education.

Locations

Jakarta Pusat, Jakarta, Indonesia

Patients applied

0 patients applied

Trial Officials

Novi Hardiany

Principal Investigator

Fakultas Kedokteran Universitas Indonesia

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported