Comparative Study Between Photodynamic Therapy with LED Associated with Probiotics in the Treatment of Halitosis

Launched by UNIVERSITY OF NOVE DE JULHO · Sep 1, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating new ways to treat halitosis, which is the medical term for bad breath. Researchers want to find out if a combination of light therapy (called photodynamic therapy) and probiotics (good bacteria that can help your mouth) can be more effective than standard oral hygiene practices alone. The study will involve 92 adults aged 18 to 60 who have been diagnosed with halitosis. To participate, individuals must show a specific level of sulfur compounds in their breath. Those with certain dental issues, on cancer treatments, or other health conditions will not be eligible.

Participants will be divided into four groups, each receiving different treatments alongside regular brushing, flossing, and tongue scraping. They will undergo breath tests and microbiological analysis at the start of the study, immediately after treatment, and again after 30 and 60 days to see how effective the treatments are. This trial is currently looking for volunteers, and it aims to not only help improve bad breath but also enhance understanding of oral health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of halitosis showing sulfhydride (SH2) ≥ 112 ppb in gas chromatography.
• Exclusion Criteria:
• • Individuals with dentofacial anomalies (such as cleft lip, cleft palate and nasopalatine);
• • Undergoing orthodontic and/or orthopedic treatment;
• • Undergoing oncological treatment;
• • With systemic alterations (gastrointestinal, renal, hepatic)
• • Undergoing antibiotic treatment up to 1 month before the research;
• • Pregnant women.