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Search / Trial NCT06585722

Association Between Venous Excess Ultrasound Grading System and Acute Kidney Injury in the ICU Population

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Sep 4, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how a new ultrasound method, called the Venous Excess Ultrasound (VExUS), can help identify patients in the Intensive Care Unit (ICU) who are at risk of fluid overload and related kidney problems. Fluid overload happens when patients receive too much fluid, which can lead to serious health issues, especially for those already in critical condition. The goal is to see if using this ultrasound can improve outcomes for ICU patients by better assessing their fluid tolerance.

To be eligible for this study, participants must be adults aged 18 or older who are expected to stay in the ICU for more than 24 hours. However, certain individuals, such as those with specific heart conditions or those who have had a kidney or liver transplant, may not be able to participate. If someone joins the trial, they can expect to undergo an ultrasound assessment to evaluate their fluid status, which could help doctors make better treatment decisions. Overall, this study aims to improve care for ICU patients who may be at risk due to fluid management.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • all patients admitted to the ICU 18 years or older expected to stay in the ICU for more than 24 hours
  • Exclusion Criteria:
  • any obstruction between the righ atrium and structures assessed by VExUS
  • a medical history of: Major cardiac shunts (e.g. atrial septum defect), Tricuspid regurgitation, dialysis, portal hypertension, pulmonary hypertension, interstitial lung disease, recipients of a kidney of liver transplant.
  • patients in whom an ultrasound assesment is unfeasible e.g. a BMI over 40

About Academisch Medisch Centrum Universiteit Van Amsterdam (Amc Uva)

The Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) is a leading academic medical center in the Netherlands, dedicated to advancing healthcare through innovative research, education, and patient care. Affiliated with the University of Amsterdam, AMC-UvA integrates clinical practice with cutting-edge biomedical research, fostering a multidisciplinary approach to medical challenges. The institution actively engages in clinical trials to enhance treatment options and improve patient outcomes, while promoting collaboration among healthcare professionals, researchers, and academic institutions globally. With a commitment to excellence and a focus on translational medicine, AMC-UvA plays a pivotal role in shaping the future of healthcare.

Locations

Amsterdam, , Netherlands

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported