The Role of Timed Awakening in Treatment of Enuresis

Launched by CHILDREN'S HOSPITAL LOS ANGELES · Sep 5, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a method called "nightly timed awakening" to help children aged 6 to 17 who experience bedwetting, known as nocturnal enuresis. The researchers want to find out if waking children up during the night to use the bathroom can help reduce bedwetting episodes. They will also look at whether other health conditions (called comorbidities) affect how well this method works, how often children have accidents during the day, and how satisfied both children and their parents are with the treatment.

To be eligible for the study, children need to be English-speaking, aged 6 to 17, and have been referred to a urology clinic for issues related to bedwetting. They must have experienced bedwetting more than once a week for over three months. Participants will be woken up by their parents at night and will also have therapy sessions using telehealth (video calls). It's important to note that children with certain medical conditions, like diabetes or those who are not potty trained, cannot join this study. This trial is not yet recruiting participants, so there will be no immediate involvement.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Our inclusion criteria are new and recently evaluated (within past 6 months) patients who are English-speaking
• • aged 6-17
• • referred to the urology clinic for enuresis (Enuresis in our study is defined as nocturnal or diurnal enuresis (more than 1 bedwetting episode/week) for greater than 3 months)
• Exclusion Criteria:
• • Diagnosis of enuresis with comorbid diagnosis of diabetes mellitus (type 1 and 2), diabetes insipidus, chronic kidney disease, polyuria and/or polydipsia
• • Structural urologic disease (evaluated via baseline imaging)
• • Diagnosis of neurodevelopmental delays or conditions (i.e. celebral palsy, autism spectrum disorder) that hinders inability to follow age-appropriate instructions
• • Not potty trained
• • Improved or resolved enuresis for patients recently evaluated (within the past 6 months)
• • Non-English speaking
• • Patients currently on any over-active-bladder (OAB) medications (b3- agonists, antichloingerics) or alpha blockers for urinary symptoms (i.e. alfuzosin, tamsulosion, etc) or anti-diurectic medications for urinary symptoms (i.e.: desmopression (DDAVP))
• • Patients currently using bed-wetting alarms
• • Patients and families who are actively seeing Pediatric Clinical Urologic Psychologist.
• • Inability or unwillingness of individual or legal guardian/representative to give written informed consent or participate in the study