VirtuAl Technology to Improve the Management of Perianal Crohn's (VAMP) - PROSPECTIVE

Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · Sep 4, 2024

Keywords

ClinConnect Summary

The VAMP trial is studying a new way to help doctors better manage a condition called perianal Crohn's disease, which can cause painful and difficult-to-treat fistulas (abnormal connections between the bowel and skin near the back passage). This trial aims to see if a new 3D visualization tool, called Virtual EUA, can help surgeons understand the anatomy of these fistulas more clearly. By improving communication between radiologists and surgeons, the goal is to make surgeries safer and more effective, potentially reducing the number of procedures patients need and improving their overall care.

To participate in the trial, patients should be between 18 and 75 years old and have active perianal Crohn's disease needing surgery. Participants will be randomly assigned to receive either the new 3D model during their care or the usual treatment. They will complete surveys before and after surgery to help researchers understand if this new approach is safe and effective. It's an exciting opportunity for eligible patients to contribute to improving care for others facing similar challenges.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Ability to give informed consent
• • Active perianal Crohn's disease as defined by clinical assessment with fistula or abscess formation
• • A clinical decision has been taken that surgery is required for perianal disease
• • Ages of 18-75
• Exclusion Criteria:
• • Inability to consent
• • history of Proctectomy,
• • absence of a diagnosis of Crohn's disease,
• • perianal fistulising disease not secondary to Crohn's disease,
• • Rectovaginal fistulas
• • Malignant disease
• • Significant cardiovascular or respiratory disease
• • Neurological or cognitive impairment
• • Significant physical disability
• • Significant hepatic disease or renal failure
• • Subjects currently (or in the last three months) participating in another research project
• • Pregnancy or breastfeeding
• • If MRI is contraindicated (e.g. pacemaker).
• • under 18 years old or over 75 years old