Modified Orbital Decompression in the Treatment of Moderate-to-severe Grave's Ophthalmopathy

Launched by SUN YAT-SEN UNIVERSITY · Sep 5, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at a specific type of surgery called modified orbital decompression to help treat people with moderate to severe Graves' ophthalmopathy, a condition that can cause bulging eyes and other eye problems due to thyroid issues. The researchers want to see how effective and safe this surgery is for improving symptoms in patients. If you or someone you know has been diagnosed with this condition and is between the ages of 18 and 75, you might be eligible to participate. To qualify, participants need to have stable thyroid levels for at least six months and a certain level of eye symptoms.

If you decide to join the trial, you will undergo surgery and be monitored closely by the medical team. They will check how well the surgery works and keep an eye on any side effects. It's important to note that individuals with serious other health problems or certain eye diseases may not be eligible to participate. This study aims to provide valuable information on how this surgery can help improve quality of life for those affected by Graves' ophthalmopathy.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. EUGOGO/NOSPECS grade was moderate-to-severe thyroid associate ophthalmopathy;
• • 2. CAS≤3 score;
• • 3. stable thyroid function for at least 6 months;
• • 4. able and willing to participate in clinical trials and ensure regular follow-up;
• Exclusion Criteria:
• • 1. any uncontrollable clinical problems (severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumors);
• • 2. B-ultrasound or CT, MRI found other diseases causing exophthalmos (intraorbital space occupying lesion, inflammatory pseudotumor, neurofibroma, etc.);
• • 3. uveitis, glaucoma, high myopia, diabetic retinopathy and other eye diseases
• • 4. those who were considered by the researchers to be excluded