B2AD-Risk AFDAS Evolution of Burden of AF
Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Sep 6, 2024
Trial Information
Current as of August 20, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The B2AD-Risk AFDAS trial is studying how atrial fibrillation (AF) develops in patients who have experienced an ischemic stroke, which is a type of stroke caused by a blockage in a blood vessel supplying blood to the brain. This trial aims to understand how AF worsens over time in stroke patients, looking at factors like heart health and new risks such as high blood pressure. Researchers will monitor participants for up to 24 months to see how often AF occurs and if certain heart markers change, which could help improve treatments in the future.
To participate in this study, you must be an adult who has had a specific type of acute ischemic stroke, either with a known history of AF or newly diagnosed AF. You cannot participate if you have a permanent or persistent form of AF, or if you have allergies to certain contrast agents used in imaging. Participants will go through regular check-ups and tests to track their heart health and the progression of AF. This research could lead to better ways to prevent strokes and manage AF for those who have had a stroke.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adult patients with cortical or subcortical, cryptogenic or non-cryptogenic acute ischemic stroke
- * Any of the following types of AF:
- • Paroxysmal AF known before stroke onset (KAF).
- • Paroxysmal AF found on an admission or Emergency Department ECG (ECG-AFDAS)
- • Paroxysmal AF found on 14-day Holter monitoring (PCM-AFDAS)
- Exclusion Criteria:
- • Patients not willing to consent
- • Permanent or persistent AF
- • Allergy to iodinated contrast agents
About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's
The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
London, Ontario, Canada
Patients applied
Trial Officials
Luciano A Sposato, MD
Principal Investigator
Western University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported