Detection of Spinal Cord Lesions Using the MP2RAGE Sequence in Inflammatory Diseases of the Neuraxis

Launched by FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD · Sep 6, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new MRI technique called the MP2RAGE sequence to improve the detection of spinal cord lesions in patients with Multiple Sclerosis (MS). Researchers want to see if this advanced imaging method can find lesions more effectively than the standard MRI techniques currently used. Detecting these lesions is important for accurately diagnosing and monitoring MS, as they often appear in difficult-to-image areas of the spinal cord, particularly in the neck region.

To participate in this trial, individuals must be over 18 years old and scheduled for an MRI of the spinal cord due to MS or related inflammatory conditions. They should also be able to give their consent and be covered by a social security scheme. Participants will undergo an MRI scan using both the new MP2RAGE technique and the usual methods, allowing researchers to compare the two. This study is currently recruiting, and it offers the opportunity for participants to contribute to important research that could improve how MS is diagnosed and managed in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient aged over 18 years
• • scheduled to undergo 1.5T or 3T MRI of the spinal cord as part of an initial assessment or reassessment of inflammatory neuraxial disease.
• • Express consent to participate in the study
• • Member or beneficiary of a social security scheme
• Exclusion Criteria:
• • Patient benefiting from a legal protection measure
• • Pregnant women
• • Absolute or relative contraindication to 1.5T or 3T MRI