Role of Endomyocardial Biopsy and Aetiology-based Treatment in Pediatric Patients with Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management (MYOPED)

Launched by SCIENTIFIC INSTITUTE SAN RAFFAELE · Sep 7, 2024

Keywords

ClinConnect Summary

The MYOPED clinical trial is studying a condition called myocarditis, which is an inflammation of the heart that can occur in children and can lead to various heart issues, including abnormal heart rhythms. This trial aims to improve how doctors diagnose and treat myocarditis by comparing different methods, including a procedure called endomyocardial biopsy (a way to take a small sample of heart tissue) and advanced imaging techniques like cardiac magnetic resonance (CMR) scans. Researchers want to learn more about how to identify the cause of myocarditis and how to manage the condition effectively, especially when it presents with heart rhythm problems.

To participate in the trial, children under 18 years old who are suspected of having myocarditis can enroll, provided they or their guardians give written consent. Participants can expect to undergo a variety of tests to help diagnose their condition and may receive specific treatments based on the findings. This trial is important because many children with myocarditis are not diagnosed correctly, and understanding this condition better could lead to improved care and outcomes for young patients with heart inflammation.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Written informed consent.
• • Age \< 18 years.
• • Clinically suspected myocarditis.
• • Enrollment performed by one of the participating Centers.
• Exclusion Criteria:
• • Absence of written informed consent.
• • Age \> 18 years (adults)