Skin Surface and Intradermal Temperature Responses to Heat Stress

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Sep 9, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating how the skin reacts to heat stress, specifically looking at the temperatures on the surface of the skin and just beneath it. The researchers want to see how these temperatures change with and without the use of cooling methods, like fans or misting. This study is important because it can help us understand how our bodies cope with heat, which is especially relevant for people who may be at risk of overheating.

To join the trial, participants should be between the ages of 65 and 74 and be generally healthy, with no serious medical conditions like heart disease, diabetes, or cancer. They should also have normal heart tests and not be taking certain medications that affect how the body regulates temperature. Women who are pregnant, breastfeeding, or planning to become pregnant are not eligible. Participants can expect to undergo tests to measure their skin temperature responses to heat, and the study is currently looking for volunteers to help with this important research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Free of any significant underlying medical problems based upon a detailed medical history and physical exam.
• • Normal resting electrocardiogram.
• Exclusion Criteria:
• • Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc.; as well as serious abnormalities detected on routine screening.
• • Individuals who are pregnant, planning to become pregnant, or breastfeeding.
• • Taking prescribed medications (such as beta blockers and non-dihydropyridine calcium channel blockers) or over-the-counter medications that have known influences on thermoregulatory response.
• • Current smokers, as well as individuals who regularly smoked within the past 3 years.