Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"

Launched by MEDICAL UNIVERSITY OF VIENNA · Sep 10, 2024

Keywords

ClinConnect Summary

The "HemodynamECMOnitoring-VV Study" is a clinical trial focusing on how to better monitor blood flow and heart function in patients receiving a treatment called venovenous extracorporeal membrane oxygenation (VV ECMO). This treatment is used for patients with severe respiratory issues like ARDS and pneumonia, where blood is taken out of the body, oxygenated through a machine, and then returned to maintain oxygen supply to vital organs. The study aims to evaluate different ways of monitoring circulation during this process to ensure patients receive the right amount of support.

To participate in this study, patients must be aged 18 to 75 and currently receiving VV ECMO support. However, those who are pregnant or have certain medical conditions that prevent them from lying down with their legs raised, such as recent trauma or high pressure in the brain, cannot join. Participants can expect to undergo various monitoring methods during their ECMO treatment, helping researchers understand which techniques are most effective. This information is crucial for improving care for patients in intensive care settings.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient receiving VV-ECMO support
• • Age 18 - 75 years
• Exclusion Criteria:
• • Pregnancy
• • Conditions not allowing for passive leg raising maneuvers, e.g. "open abdomen", known or suspected elevation of intracranial pressure, recent leg or spinal trauma or orthopedic conditions not permitting leg raising
• • Known ischemic or hemorrhagic stroke within 3 months prior to study enrollment.
• • Suspicion of raised intracranial pressure is defined as pupil divergence (if not yet further clarified radiographically/neurologically/ophthalmologically) or signs detected in routine computed tomography scans (compressed or elapsed basal cisterns or midline shift \> 5 mm.