A Feasibility Randomized Trial Evaluating Early vs Late Stent Removal Following Radical Cystectomy and Ileal Conduit Formation for Bladder Cancer

Launched by WESTERN UNIVERSITY, CANADA · Sep 10, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring whether removing a ureteric stent earlier (5-7 days after surgery) is better than removing it later (4-6 weeks after surgery) for patients who have undergone surgery for bladder cancer. The stent is a small tube placed in the ureter (the tube that carries urine from the kidney to the bladder) to help prevent complications like urinary leakage or blockages after the surgery. Researchers want to see if early removal can reduce the chances of complications like urinary tract infections and hospital readmissions.

To participate in this trial, you need to be an adult (18 years or older) who is having a radical cystectomy and ileal conduit formation, which is a type of surgery for bladder cancer. However, if your treatment is not intended to cure the cancer or if you have received previous radiation therapy in the relevant area, you may not be eligible. If you join the trial, you will be randomly assigned to either the early or late stent removal group, and you can expect close monitoring during your recovery. This study hopes to provide clearer answers about the best approach to stent removal after this type of surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patients (18 years or older) undergoing radical cystectomy and ileal conduit formation for bladder cancer
• • Able to give informed written consent to participate.
• Exclusion Criteria:
• • Treatment without curative intent (cT4b, salvage or palliative cystectomies);
• • Patients undergoing alternative forms of urinary diversion (e.g. continent cutaneous urinary diversion or orthotopic neobladder formation)
• • Patients previously received abdominal/pelvic radiotherapy
• • Patients with concomitant upper urinary tract cancer