Clinical Outcomes of Thoracodorsal Artery Flap in Oral and Maxillofacial Reconstruction

Launched by SUN YAT-SEN MEMORIAL HOSPITAL OF SUN YAT-SEN UNIVERSITY · Sep 13, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at different types of surgical flaps used to help reconstruct the face after removing tumors caused by oral squamous cell carcinoma (OSCC), a type of mouth cancer. Specifically, the study will compare the thoracodorsal artery perforator flap, a specific type of flap, with other flaps like the anterolateral thigh flap and fibula flap. Researchers want to find out if the thoracodorsal flap leads to better recovery outcomes, such as improved speech, better quality of life, and less noticeable scarring.

To participate in this trial, you need to have been diagnosed with oral squamous cell carcinoma and undergone surgery to remove the tumor and reconstruct your face at the hospital conducting the study. You’ll need to complete several check-ups and questionnaires at 1, 3, 6, and 12 months after your surgery to help the researchers understand how well the different flaps are working. This study aims to find the best option for patients like you, so your input will be very valuable.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with oral squamous cell carcinoma who have completed comprehensive imaging examinations before surgery.
• • 2. Preoperative pathological biopsy confirmed as oral squamous cell carcinoma.
• • 3. Patients with oral squamous cell carcinoma who have completed comprehensive laboratory tests before surgery.
• • 4. Patients with oral squamous cell carcinoma who underwent tumor resection and flap reconstruction at our hospital.
• • 5. Postoperative pathological diagnosis confirmed as oral squamous cell carcinoma.
• • 6. Patients with oral squamous cell carcinoma who attend follow-up visits at 1, 3, 6, and 12 months post-surgery, completing all clinical examinations and questionnaires.
• Exclusion Criteria:
• • 1. Patients with oral squamous cell carcinoma who lack imaging data or have artifacts affecting imaging results.
• • 2. Patients with oral squamous cell carcinoma who have incomplete laboratory test results from our hospital.
• • 3. Patients with oral squamous cell carcinoma with postoperative pathology that remains unclear or cannot be confirmed as oral squamous cell carcinoma.
• • 4. Patients with oral squamous cell carcinoma who are unable to attend follow-up visits at 1, 3, 6, and 12 months.
• • 5. Patients who do not complete the questionnaires as required during follow-up visits.