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Search / Trial NCT06600568

Novel Therapeutic Approach for Human T-cell Malignancies

Launched by ISTITUTO ONCOLOGICO VENETO IRCCS · Sep 16, 2024

Trial Information

Current as of July 04, 2025

Recruiting

Keywords

T Cell Lymphoblastic Leukemias (T All) T Cell Non Hodgkin's Lymphomas (T Nhl) Nk Cell Neoplasia Ros Apoptosis

ClinConnect Summary

This clinical trial is exploring a new treatment approach for adults with T-cell leukemia and lymphoma, which are types of blood cancers. Researchers are looking for ways to specifically target and eliminate the harmful T-cells by adjusting certain levels within the cells. They will study the effects of different drug combinations, including one that encourages cancer cells to die and another that helps balance cell functions. The goal is to find the most effective treatments that can then be tested on patients whose cancer has not responded to standard treatments.

To participate in this trial, individuals must be over 18 years old and have been diagnosed with T-cell leukemia or lymphoma. Both men and women are eligible, but participants need to be in a condition that allows them to follow standard treatment protocols. If you join the study, you can expect to see how these promising new drugs work on your specific cancer cells in a supportive and monitored environment. This trial is currently recruiting participants, and your involvement could contribute to important advancements in cancer treatment.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with pre- and post-thymic T-cell leukemia/lymphoma
  • Patients of both sexes
  • Age of patients older than 18 years
  • Patient is willing to provide written and signed informed consent for participation in the study
  • Exclusion Criteria:
  • -Serious illness or medical condition that does not allow the patient to be managed according to standard treatment protocols, including uncontrolled active infection.

About Istituto Oncologico Veneto Irccs

Istituto Oncologico Veneto IRCCS is a leading cancer research and treatment institution located in Italy, dedicated to advancing oncological science and improving patient outcomes. As an IRCCS (Istituto di Ricovero e Cura a Carattere Scientifico), it combines clinical excellence with cutting-edge research, focusing on innovative therapies and comprehensive cancer care. The institute plays a pivotal role in the development and execution of clinical trials, fostering collaboration among researchers, healthcare professionals, and patients to translate scientific discoveries into effective treatment strategies. Through its commitment to high-quality research and patient-centered care, Istituto Oncologico Veneto IRCCS aims to enhance the understanding and treatment of cancer on both a national and international scale.

Locations

Padova, , Italy

Napoli, , Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported