Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis

Launched by AIN SHAMS UNIVERSITY · Sep 15, 2024

Keywords

ClinConnect Summary

This clinical trial is investigating the use of a gel made from rosemary extract to help manage periodontitis, a serious gum disease that can lead to tooth loss. The rosemary extract has natural properties that can fight bacteria and reduce inflammation, making it a potential helpful treatment when combined with standard dental care. The study aims to see how effective this gel is for people with stage 3 periodontitis, particularly those with deep pockets in their gums where bacteria can thrive.

To participate in this trial, individuals must be healthy adults aged 25 to 45 years, with specific types of gum disease affecting their back teeth. However, smokers, pregnant or nursing women, and those with certain health issues or allergies to rosemary cannot join. Participants can expect to use the rosemary gel as part of their oral care routine, and they will need to follow good hygiene practices. This trial is not yet recruiting, so interested individuals will need to wait for the study to start.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Both genders aged between 25-45 years.
• • 2. Healthy adult patients as evidenced by Burket's oral medicine health history questionnaire.
• • 3. Stage III grade B periodontitis with at least two non-adjacent sites in posterior teeth with PD ≥ 6 mm, CAL ≥ 5 mm showing BOP and ≤ 4 teeth lost due to periodontitis.
• • 4. Patients ready to comply with oral hygiene measures.
• Exclusion Criteria:
• • 1. Smokers.
• • 2. Pregnant or lactating females.
• • 3. Drug abusers.
• • 4. Patients taking antibiotics or performed any periodontal treatment in the previous 6 months.
• • 5. Patients who have a known allergy or hypersensitivity to rosemary, its constituents, or other members of the Lamiaceae family.
• • 6. Patients with parafunctional habits.