Hybrid Score to Predict OTVA-SOO in Patients with Wide Basal QRS

Launched by CENTRO MEDICO TEKNON · Sep 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to predict the origin of outflow tract ventricular arrhythmia (OTVA), which is a common heart rhythm issue. The goal is to improve the effectiveness of catheter ablation, a procedure used to treat this condition. Researchers developed a scoring system called the Hybrid Score that combines information from patients’ medical history and electrocardiograms (ECGs), which are tests that record the electrical activity of the heart. This study specifically focuses on patients who have a wide QRS complex, meaning their heart's electrical signals are delayed due to conditions like intraventricular conduction defects or the presence of a pacemaker.

To be eligible for the trial, participants must have symptoms of ventricular arrhythmia with a specific ECG pattern indicating that the issue likely originates from the outflow tract, and their QRS width must be greater than 110 milliseconds. Those who join the trial will have their heart activity monitored and will undergo the catheter ablation procedure if appropriate. The trial is open to all genders, and participants will need to provide written consent. This study aims to gather valuable data to help refine the Hybrid Score and ultimately improve treatment outcomes for patients with this type of heart rhythm disorder.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ventricular arrhythmia with a morphology indicating an outflow tract origin and a wide basal QRS complex
• • a QRS width greater than 110 ms was considered wide
• • willing and capable of providing written informed consent to the study
• Exclusion Criteria:
• • catether ablation procedure was unsuccessful
• • infrequent arrhythmia requiring ablation guided by pacemapping.