Microplastics in the Human Respiratory System

Launched by WIELKOPOLSKIE CENTRUM PULMONOLOGII I TORAKOCHIRURGII · Sep 17, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the presence of tiny plastic particles, known as microplastics, in the lungs of patients with lung cancer and other respiratory diseases. Microplastics can come from the breakdown of larger plastic items and can enter our bodies through the air we breathe. Researchers want to learn more about how these particles may affect lung health, as there are concerns they could cause inflammation and possibly contribute to lung diseases, including lung cancer. The study aims to collect tissue samples during surgeries to see how common these microplastics are and what types are found in the lungs.

To participate in this trial, individuals must be 18 years or older and undergoing surgery for lung cancer, emphysema, interstitial lung diseases, or lung transplantation. However, those who have recently undergone certain treatments like chemotherapy or radiation, or who have had previous lung surgeries, may not be eligible. Participants will have their lung tissue analyzed for microplastics, which could help researchers gain a better understanding of the potential health impacts of these particles. This study is important because it may provide insights into how environmental pollution affects our respiratory health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients undergoing surgery for lung cancer, emphysema, interstitial lung diseases, or other respiratory conditions,
• • patients undergoing lung transplantation (lungs removed from transplant recipients),
• • age 18 years or older,
• • ability to provide informed consent.
• Exclusion Criteria:
• • patients with a history of recent or ongoing chemotherapy, immunotherapy, or radiation therapy,
• • inability or unwillingness to provide informed consent,
• • previous lung surgeries,
• • insufficient tissue or blood samples available for analysis due to technical or procedural reasons.