Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index

Launched by NAMIK KEMAL UNIVERSITY · Sep 18, 2024

Keywords

ClinConnect Summary

This clinical trial is looking into how testosterone therapy affects the level of anesthesia during surgery for a condition called hypospadias, which is a birth defect affecting the urethra in boys. Researchers want to see if giving testosterone before or during surgery changes how deep the anesthesia needs to be. This study will also monitor the patients’ breathing while they are under general anesthesia, using a special device called BIS (Bispectral Index) that helps measure consciousness levels.

The trial is open to boys aged 1 to 16 who are healthy enough for surgery (classified as ASA I) and are scheduled for hypospadias repair. However, it will not include those who are very overweight or have other health issues. If eligible, participants can expect to undergo their usual surgery with some additional monitoring and data collection to help understand the effects of testosterone on anesthesia. It's important to note that the trial is not yet recruiting participants, so there will be a waiting period before it begins.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Ages 1-16
• • Patients with ASA I (Normal healthy patients except for surgery)
• • Patients who will undergo surgery for hypospadias repair
• Exclusion Criteria:
• • Morbidly obese patients (body mass index \> 40kg/m2)
• • ASA II-III-IV patients (other groups of patients with additional diseases)
• • Volunteers who do not want to participate in the study