Study of Yupingfeng Powder Treating Allergic Rhinitis (AR)

Launched by CHINESE UNIVERSITY OF HONG KONG · Sep 19, 2024

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness and safety of a traditional Chinese herbal medicine called Yupingfeng Powder for treating allergic rhinitis (AR), a common condition that causes symptoms like a runny nose, sneezing, and nasal congestion. While many people currently use western medications like steroids and antihistamines for relief, these treatments don’t work well for everyone. This study aims to see if Yupingfeng Powder can help improve symptoms and overall quality of life for patients with AR.

To take part in the trial, participants must be at least 18 years old, have certain symptoms of AR for more than an hour each day, and be willing to provide written consent. However, individuals with serious health conditions or those who have recently taken certain medications may not be eligible. If you join the study, you will receive either Yupingfeng Powder or a placebo (a non-active substance) twice a day for eight weeks. After that, there will be an additional eight weeks of follow-up to see how long the effects last. The trial is not yet recruiting participants, but it aims to provide strong evidence about the potential benefits of this herbal treatment for allergic rhinitis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18 or above;
• • Subjects with deficiency of lung and spleen Qi;
• • At least 2 or more allergic symptoms (rhinorrhea, sneezing, nasal obstruction and nasal itching) for a cumulative period greater than 1 hour per day;
• • Understand Chinese;
• • Voluntary written consent.
• Exclusion Criteria:
• • Known chronic disease such as asthma, rhinosinusitis, nasal polyposis;
• • Known severe medical conditions, such as cardiovascular, liver or renal dysfunction, diabetes mellitus, cancers, cerebrovascular diseases, blood system diseases;
• • Concomitant steroid, nonsteroidal anti-inflammatory drugs (NSAIDs), anticoagulant, and immunotherapy within past month;
• • Impaired hematological profile and liver / renal function exceeds the upper limit of the reference value by 2 times ;
• • Known alcohol and / or drug abuse;
• • Known allergic history to any Chinese herbal medicines;
• • Known pregnant or lactating.