Restoration of Antibiotics Related Infant Microbiota Perturbations by Autologous Fecal Transplant

Launched by RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY · Sep 19, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help restore the healthy gut bacteria in young children who have taken antibiotics. Antibiotics are important medicines that fight infections, but they can also disrupt the balance of good bacteria in the gut, which may lead to health issues later in life, such as allergies or obesity. The researchers believe that by collecting a sample of a child’s gut bacteria before they take antibiotics and then giving it back to them afterward through a simple method (mixing it with milk or formula), it might help their gut bacteria recover more quickly and completely.

The trial is looking for healthy infants and toddlers between 1 month and 4 years old. To participate, children should not have taken antibiotics in the past three months and should not have any documented immune system conditions. If eligible, families can expect a straightforward process that aims to help their child's gut health without causing any discomfort. This innovative approach could help improve the long-term health of young children who need antibiotics.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • healthy infants and toddlers 1 month to 4 years of age (regardless of birth mode, sex, or diet (breastmilk, formula, solids, etc.)
• Exclusion Criteria:
• • Child's antibiotic use within 3 months before inclusion in the study
• • Documented immunological condition from the child's pediatrician