Search / Trial NCT06611280

Deuterium Metabolic Imaging in People with Multiple Sclerosis

Launched by UNIVERSITY OF AARHUS · Sep 20, 2024

Trial Information

Current as of December 22, 2024

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking to understand how the brain uses glucose (a type of sugar) in people with relapsing-remitting multiple sclerosis (MS) compared to healthy individuals of similar age and gender. Researchers want to find out if there are differences in brain glucose metabolism and how these differences relate to the severity of MS symptoms. By studying these factors, the trial aims to gain insights that could help improve the understanding and treatment of MS.

To participate in this study, individuals need to be between 18 and 60 years old and have a confirmed diagnosis of relapsing-remitting MS. Those interested will spend about three hours at the testing site, where they will undergo a special imaging procedure called deuterium metabolic imaging, along with tests to assess physical and cognitive function, and complete a survey. It's important to note that certain conditions, like having a pacemaker or being pregnant, may prevent someone from participating. This trial is currently recruiting participants, and researchers are looking forward to gathering valuable information that could benefit people living with MS.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Aged 18-60 years.
  • Definite Relapsing remitting multiple sclerosis diagnosis according to the most recent diagnostic criteria
  • Exclusion Criteria:
  • * Contraindications for MRI:
  • Pacemaker, neurostimulator or cholera implant. Metal foreign bodies such as fragments and irremovable piercings. Unsafe medical implants (safety of heart valves, hips and the like must be confirmed).
  • Claustrophobia. Largest circumference including arms \> 160 cm
  • Pregnancy
  • Competing neurological, psychiatric, or systemic diseases including diabetes (except prior TIA, unspecific brain MRI findings, hypertension, atherosclerosis and hyperlipidemia/cholesterolemia which are allowed).
  • Participating in other clinical trials with investigational medical products or drugs.

About University Of Aarhus

The University of Aarhus, a prestigious research institution located in Denmark, is dedicated to advancing medical science through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters an environment that encourages cutting-edge research and the development of novel therapeutic interventions. Committed to ethical standards and patient safety, the University of Aarhus aims to contribute to the global body of medical knowledge while enhancing healthcare outcomes through rigorous scientific inquiry and evidence-based practices.

Locations

Aarhus C, , Denmark

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0