Effect of Inspiratory Muscle Training on Ventilated Patients in an Intensive Care Unit
Launched by CHANG GUNG UNIVERSITY · Sep 22, 2024
Trial Information
Current as of June 23, 2025
Completed
Keywords
ClinConnect Summary
Patients on mechanical ventilation often experience rapid diaphragm atrophy on the second day, resulting in muscle fiber changes, respiratory muscle weakness. Clinical studies have explored enhancing diaphragm and respiratory muscle strength and endurance through inspiratory muscle, expiratory muscle, and combined respiratory muscle training. This study was to determine if inspiratory muscle training significantly facilitates liberation from mechanical ventilation and improves muscle strength when compared to without IMT among subacute critically ill adult patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • requiring invasive mechanical ventilation for 2 days in an ICU
- Exclusion Criteria:
- • hemodynamic instability (heart rate 120 beats/min, unstable blood pressure, vasopressor infusion)
- • inadequate oxygenation (PEEP 8 cmH2O, FiO2 50%)
- • body temperature 38.5°C
- • sepsis
- • use of sedative infusion
- • steroid administration
- • home ventilator use before ICU admission
About Chang Gung University
Chang Gung University, located in Taiwan, is a leading institution dedicated to advancing medical research and education. Renowned for its commitment to innovation and excellence in healthcare, the university actively sponsors clinical trials aimed at improving patient outcomes and contributing to the global body of medical knowledge. With a multidisciplinary approach, Chang Gung University collaborates with various healthcare professionals and researchers to explore novel therapies and interventions across a range of medical fields, ensuring that its clinical research initiatives adhere to the highest ethical and scientific standards.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kaohsiung, , Taiwan
Patients applied
Trial Officials
Shu-Jane Wang, MS
Study Director
Zuoying Armed Forces General Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported