Biliary Fistulas in Surgery of Liver Echinococcosis

Launched by REPUBLICAN SPECIALIZED SCIENTIFIC AND PRACTICAL MEDICAL CENTER OF SURGERY NAMED AFTER V. VAKHIDOV · Sep 21, 2024

Keywords

ClinConnect Summary

This clinical trial is focused on improving surgical treatments for patients with liver echinococcosis, a type of infection caused by a parasite. Specifically, it looks at cases where surgery leads to a complication known as a biliary fistula, which is an abnormal connection between the bile ducts and other structures. The goal is to enhance how doctors diagnose this complication early and to refine the surgical techniques used to address it, ultimately aiming for better recovery outcomes for patients.

To be eligible for this study, participants must be 18 years or older and have liver echinococcosis that requires surgery. They should also have completed all necessary preoperative tests and be willing to provide informed consent to participate. Those who join can expect to undergo standard surgical procedures, with close monitoring of their recovery process. The study will track various aspects of their health during and after surgery for up to three months, helping researchers understand the best ways to manage this condition and its complications.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age under 18 years;
• • Informed consent for inclusion in the study;
• • The presence of liver echinococcosis, for which conservative surgical treatment will be performed;
• • The presence of the entire spectrum of necessary preoperative diagnostic measures;
• • A full description of all stages of surgical intervention, indicating the type of intervention (open or laparoscopic surgery, location and size of the echinococcal cyst in the liver, type of antiparasitic treatment, presence or absence of a biliary fistula in the residual cavity, actions taken in relation to the fistula, the option of eliminating the residual cavity and drainage;
• • Availability of objective data on the characteristics of the postoperative course, including dynamic indicators of the patient\'s condition, temperature, amount and nature of discharge through the drainage, the time of drainage removal, the type of complications (if any) and the method of their treatment, the duration of the hospital period, data on the characteristics of the posthospital period up to 3 months of observation;
• • Absence of concomitant pathology that may affect the outcome of the surgery.
• Exclusion Criteria:
• • Age under 18 years;
• • Refusal to participate in the study;
• • Extrahepatic echinococcosis without liver damage;
• • Absence of the full range of preoperative diagnostic data;
• • Difficulties with objective analysis of the features of the performed surgical treatment;
• • Incomplete data on monitoring the postoperative hospital and remote (up to 3 months) period;
• • The presence of concomitant pathology that may affect the outcome of the operation.