Effects of 60-day-6° Head-down Bed Rest on Cartilage and Function of the Knee Joint

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Sep 24, 2024

Keywords

ClinConnect Summary

This clinical trial is examining how spending 60 days lying in a head-down position (like being in a zero-gravity environment) affects the knee joint's cartilage and overall function. Researchers want to understand how this type of bed rest, which simulates the feeling of weightlessness, impacts the quality of the cartilage in the knee. They will use advanced imaging technology to study these effects.

To participate in this trial, you need to be a male aged between 25 and 50, with a height of 160-175 cm and a weight of at least 50 kg. You should also have a healthy general condition. If you have a history of alcohol or drug issues, smoke heavily, or have certain health conditions like severe vertigo, you won't be eligible. If you join, you can expect to be part of a study that aims to help scientists learn more about how our bodies respond to prolonged bed rest, which can be important for understanding health in space travel and other situations where movement is limited.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • (1) male; (2) age 25-50 years old; (3) height between 160-175 cm, weight ≥50kg, and BMI between 18.5-26 kg/m²; (4) good general health status.
• Exclusion Criteria:
• • (1) history of alcoholism; (2) smoking ≥5 cigarettes/day in the 3 months before the test; (3) drug dependence or use of medications affecting bone metabolism within 2 weeks before screening; (4) presence of metal implants, severe vertigo, or severe snoring.