Vaccine-induced Immunity in Immunocompromised Patients

Launched by UNIVERSITY OF COLOGNE · Sep 21, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how well vaccines work in patients with weakened immune systems, particularly those who have conditions like blood disorders or are undergoing treatments that affect their immune response. The researchers want to understand how booster vaccinations can help these patients fight off respiratory virus infections, focusing on the body’s T cell responses, which play a key role in protecting against infections.

To participate in this study, patients must be 18 years or older and have some form of immunosuppression, either from their medical treatment or their underlying health conditions. They should also be willing to receive a vaccine against respiratory viruses. Participants will be monitored after their vaccinations to see how their immune systems respond. This trial is currently recruiting and aims to improve our understanding of vaccination effectiveness in vulnerable patients, which could ultimately help in managing their health better.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent form
• • Patients with immunosuppression either by treatment or underlying diseases
• • Patients who are vaccinated or willing to be vaccinated against respiratory virus infections in ac-cordance with current recommendations
• • Age of 18 years or older
• Exclusion Criteria:
• • Patients unwilling/ineligible for vaccination under current recommendations