High vs Low-frequency of High-intensity Training in Chronic Stroke

Launched by INDIANA UNIVERSITY · Sep 22, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how often people with chronic stroke should participate in high-intensity training to improve their walking ability. The researchers want to see if training more frequently leads to better outcomes compared to training less often. The study is currently recruiting participants aged 18 to 85 who have had a stroke more than six months ago and have some difficulties with movement on one side of their body. To be eligible, participants should be able to walk with some assistance and follow simple commands.

If you or a loved one qualifies for this study, you will be asked to participate in a walking program that includes both supervised training sessions and exercises you can do at home. It’s important to note that certain medical conditions, previous injuries, or current participation in other physical therapies may prevent someone from joining this trial. Overall, this study aims to help improve walking skills in stroke survivors, which could potentially enhance their daily life and independence.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Unilateral deficits following stroke \> 6 months prior; however individuals \> 4 months post-stroke are eligible for consenting, but final eligibility and potential enrollment will not occur until \> 6 months
• • Age 18-85
• • Weight \< 350 pounds
• • Able to follow 3-step commands
• • Able to ambulate with self-selected gait speeds between 0.10-1.0 m/s without physical assistance, but with below knee bracing and/or assistive device as needed
• • Lower extremity Fugl-Meyer \< 34
• • Medical clearance to participate
• Exclusion Criteria:
• • Evidence of cerebellar ataxia
• • Uncontrolled cardiopulmonary or metabolic disease that limits exercise participation, active heterotopic ossification, recurrent history of lower extremity fractures, previous orthopedic or other peripheral or central neurologic injury that may impair locomotor activities such that, in the judgement of the PI, could compromise the safety of the participant, limit the ability to complete the study, or compromise the objectives of the study.
• • Currently participating in other physical therapy
• • \>50 units of Botox in the lower extremity OR in the lower extremity, but above the knee if the participant wears an ankle-foot-orthosis (AFO) within the past three months

Trial Officials