Search / Trial NCT06613542

Effects of Daily Taurine Intake for 6 Months on Biological Age and Body Metabolism Indicators As Well As Physical Fitness in 55-75-year-old Women and Men

Launched by TECHNICAL UNIVERSITY OF MUNICH · Sep 22, 2024

Trial Information

Current as of October 07, 2024

Not yet recruiting

Keywords

Taurine Biological Aging Metabolic Health Anti Aging Epigenetic Clock Aging Physical Activity Cognition Cellular Senescence Hallmarks Of Aging Humans Dietary Supplements Longevity Taurine Deficiency Taurine Level Aging Metabolism Longevity Physiology Drug Effects Dna Methylation Aging Ptoeomics Dna Methylation Taurine Microbiome Taurine Gut Micorbiota Taurine Cognition Taurine Sport Taurine Dna Methylation Nutritional Medicine Sport Biology Taurine Physical Fitness Taurine Physical Acitvity Taurine Sport Biology Taurine Muscle Strength Taurine Pwc 130 Taurine Homa Ir Taurine Mental Health Taurine Human Aging Taurine Cardiometabolic Risk Taurine Cardiometabolic Health Taurine Blood Pressure Taurine Fasting Glucose Taurine Inflammation Taurine Biological Aging

Description

Measurements performed during study visits: * Biological age estimate via proteome analysis * Organ age estimates (proteomics) * DNA methylation * Inflammatory biomarkers (CRP, cytokines) * Metabolic variables: fasting blood glucose, insulin, HOMA-IR, HbA1c, lipids, BMI * Physical fitness (hand grip strength, leg extensor strength, PWC130) * Resting energy expenditure * Cognitive function via questionnaire * Quality of life * Heart rate variability * Physical activity, nutrition

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * women or men
  • * Age 55 - 75
  • * BMI 22 - 30 kg/m²
  • * written consent
  • Exclusion Criteria:
  • * Acute or chronic inflammation (e.g. flu infection)
  • * Severe chronic illness (e.g., Type 1 or Type 2 diabetes mellitus, COPD, renal insufficiency)
  • * Myocardial infarction or stroke in the previous 6 months
  • * Psychiatric disorder, including depression or dementia
  • * Weight change of ≥ 5 kg in the last 6 months

About Technical University Of Munich

The Technical University of Munich (TUM) is a leading research institution in Germany, renowned for its commitment to excellence in education, innovation, and technology transfer. With a strong emphasis on interdisciplinary collaboration, TUM fosters advancements in various fields, including medicine and life sciences. The university actively engages in clinical research, aiming to translate scientific discoveries into practical applications that improve patient outcomes. Through its state-of-the-art facilities and a network of partnerships with hospitals and industry, TUM is dedicated to conducting rigorous clinical trials that adhere to the highest ethical standards and contribute significantly to the advancement of healthcare.

Locations

Munich, , Germany

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0