Search / Trial NCT06613932

Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars

Launched by FUTURE UNIVERSITY IN EGYPT · Sep 25, 2024

Trial Information

Current as of December 22, 2024

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for young adults with irreversible pulpitis, a painful condition affecting the pulp (the inner tissue) of mature mandibular first molars (the large back teeth). The researchers are looking at a combination of two materials: L-PRF (a type of platelet-rich fibrin that helps with healing) and nanohydroxyapatite (a substance that mimics natural bone). The goal is to see how well this combined treatment works in helping to preserve the tooth and promote healing.

To be eligible to participate, you should be between 15 and 30 years old, in good health, and willing to agree to follow-up visits for six months after the treatment. Your tooth needs to be restorable and show signs of irreversible pulpitis but must not have any serious issues like infections or root damage. If you decide to participate, you'll receive the treatment and then have regular check-ups to assess how well the procedure worked. This may be an opportunity to contribute to important research while receiving care for your dental condition.

Gender

ALL

Eligibility criteria

  • Inclusion criteria:
  • Patients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn\'t contain any internal or external resorption or periapical lesions.
  • The tooth should give a positive response to the cold test.
  • Exclusion criteria:
  • Pregnant and lactating females. Patients with Mental disturbance. Patients who could/would not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy

Trial Officials

wael K hussein, professor

Study Director

future

About Future University In Egypt

Future University in Egypt is a leading academic institution dedicated to advancing medical research and education. As a clinical trial sponsor, the university focuses on innovative studies that aim to enhance healthcare outcomes and address pressing medical challenges. With a commitment to ethical standards and scientific rigor, Future University collaborates with healthcare professionals and researchers to facilitate evidence-based practices and contribute to the global body of medical knowledge. Its strategic initiatives aim to foster a culture of research excellence, ultimately benefiting both local and international communities.

Locations

Cairo, New Cairo, Egypt

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0