Search / Trial NCT06614348

Prednisolone Acetate Eye Drops for Pain Intervention in Second Eye Cataract Surgery

Launched by SHANGHAI GENERAL HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE · Sep 24, 2024

Trial Information

Current as of October 08, 2024

Not yet recruiting

Keywords

Cataract Surgery Pain Second Eye Cataract Surgery

Description

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Age between 50-80 years old;
  • * A clear diagnosis of age-related cataract, having completed the first eye cataract surgery at our hospital, and planning to have the second eye cataract surgery with the same doctor;
  • * The interval between the two surgeries is ≤30 days;
  • * Capable of cooperating to complete iris optical coherence tomography angiography examination;
  • * Based on our team\'s previous research, a predictive scoring formula for pain during the second eye surgery has been derived (Predicted score = 1.36 + 4.93 \* preoperative iris vessel area density - 0.24 \* surgical interval (weeks)), and the calculated predicted score is \>2.
  • Exclusion Criteria:
  • * History of ocular trauma, ocular surgery, uveitis, fundus disease, glaucoma, or recent history of episcleritis, keratitis, severe dry eye, and other ocular surface disease episodes;
  • * Participation in intraocular or systemic medication clinical trials within the past 6 months;
  • * Having an autoimmune disease or currently undergoing immunosuppressive therapy;
  • * Having a psychiatric disorder such as anxiety or depression;
  • * History of using glucocorticoid eye drops for treatment in the second eye within the past month;
  • * Long-term use of drugs that can cause intraoperative floppy iris syndrome, such as alpha-blockers;
  • * Severe complications occurred during or after the first eye surgery (e.g., posterior capsule rupture, zonular exercise, nuclear drop into the vitreous cavity, postoperative endophthalmitis, glaucoma, etc.).

About Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

Shanghai General Hospital, affiliated with Shanghai Jiao Tong University School of Medicine, is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, the hospital leverages its extensive expertise in various medical specialties to conduct rigorous and ethical trials aimed at improving patient outcomes. With a focus on collaboration and scientific integrity, Shanghai General Hospital plays a pivotal role in the development of new therapies and interventions, contributing significantly to the global healthcare landscape.

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Timeline

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Trial launched

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Estimated completion

Not reported

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