ClinConnect ClinConnect Logo
Search / Trial NCT06614426

Surgical Treatment of Peri-implantitis Defects

Launched by ABEER HAKAM · Sep 25, 2024

Trial Information

Current as of July 24, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to treat a dental condition called peri-implantitis, which occurs when there is inflammation and infection around dental implants. The study will test a cleaning method that uses a special process called electrolysis to clean the implant surfaces, and will also check if adding L-PRF, a treatment that helps with healing, can improve recovery and keep the bone around the implant healthy over time.

To participate in this trial, you need to be at least 18 years old and diagnosed with peri-implantitis, which shows up as bleeding and deep pockets around the implant. You should also have a screw-retained implant crown and be willing to attend follow-up appointments. Unfortunately, people with certain health issues, such as those who have had previous surgeries for peri-implantitis or are currently on antibiotics, cannot join. If you decide to participate, you will be helping researchers learn more about how to effectively treat this condition and improve outcomes for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Aged 18 or over.
  • Require treatment of peri-implantitis (defined as the presence of bleeding and/or suppuration on gentle probing, probing depths of ≥ 6 mm, presence of bone loss beyond crestal bone level changes resulting from initial bone remodeling).
  • Screw retained implant crown.
  • Good compliance and commitment to attend follow-up review appointments.
  • Willing to provide informed consent.
  • Exclusion Criteria:
  • History of surgical therapy of peri-implantitis.
  • Peri-implant defects indicated for regenerative procedure (i.e. contained bony defect).
  • Cement retained implant crown.
  • Systemic/local antibiotics during the previous 6 months.
  • Bone metabolic disease and/or taking medications that affect bone metabolism.
  • History of malignancy, radiotherapy or chemotherapy.
  • Pregnant or lactating women.
  • Smokers

About Abeer Hakam

Abeer Hakam is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes through innovative therapies. With a focus on precision medicine, Abeer Hakam collaborates with leading research institutions and healthcare professionals to design and implement rigorous clinical trials. The organization prioritizes ethical standards, patient safety, and regulatory compliance, ensuring that all studies adhere to the highest scientific and ethical guidelines. By fostering collaboration and leveraging cutting-edge technologies, Abeer Hakam aims to accelerate the development of transformative treatments and contribute to the global healthcare landscape.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported