Search / Trial NCT06615765

Acupuncture for Symptom Relief in Adults with Mild to Moderate Ulcerative Colitis

Launched by GUANG'ANMEN HOSPITAL OF CHINA ACADEMY OF CHINESE MEDICAL SCIENCES · Sep 24, 2024

Trial Information

Current as of October 04, 2024

Not yet recruiting

Keywords

Acupuncture Ulcerative Colitis Patient Reported Outcome 2 Inflammatory Bowel Disease Randomized Controlled Trial

Description

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by episodes of symptoms including rectal bleeding, increase stool frequency, and abdominal pain, impacting quality of life significantly. Conventional treatments often come with potential side effects and may not be sufficient. Acupuncture is increasingly recognized for its promising benefits in UC. This study aims to assess the efficacy and safety of acupuncture for symptom relief in mild to moderate UC.This single-center, parallel-arm, randomized, sham-controlled trial will involve 64 patients with UC, randomly ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Eligible participants are those aged 18 to 70 years who meet the diagnostic criteria for mild to moderate UC, have a PRO2 score of ≥ 2 points, and provide written informed consent. Patients currently receiving oral and/or topical 5-aminosalicylic acid (such as mesalamine) may continue their treatment during the study period.
  • Exclusion Criteria:
  • Participants will be excluded if they meet any of the following criteria:
  • 1. Diagnosis of Crohn's disease, intestinal tuberculosis, chronic intestinal infections, or intestinal malignancies.
  • 2. Current treatment with corticosteroids, thiopurines, biologics, or oral small molecules.
  • 3. Severe skin conditions or infections.
  • 4. Presence of severe underlying medical conditions, including but not limited to cardiovascular diseases, hepatobiliary diseases, kidney diseases, hematologic disorders, autoimmune diseases, communicable diseases, severe malnutrition, or malignancies.
  • 5. Mental illness, cognitive dysfunction, or language disorders.
  • 6. Receipt of acupuncture therapy for UC within the past month.
  • 7. Substance abuse issues.
  • 8. Pregnancy, plans to become pregnant within the next year, lactation, or being within 12 months postpartum.

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0