Search / Trial NCT06616688

Innovative Therapeutic Treatments to Inhibit Perineural Invasion in Pancreatic Adenocarcinoma

Launched by IRCCS SAN RAFFAELE · Sep 25, 2024

Trial Information

Current as of October 07, 2024

Not yet recruiting

Keywords

Description

STUDY DESIGN The overarching goal of this project is to develop new therapeutic approaches to limit PNI formation and therefore PDAC formation and metastasis. PNI, has its higher incidence in PDAC, in which it is a recognized risk factor of poor survival. Considering the clinical relevance of PNI and its role in PDAC, it is urgent to identify molecular PNI signatures to develop new therapeutic strategies. We have recently identified a molecule (FGFBP1) that is activated in pancreatic cancer cells and initiate PNI. This project is designed as an observational multicentric, cross-sectional s...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Age \>18 years (also fertile patients ca be included)
  • * Surgical resection for suspected PDAC, as per clinical practice. We will use this material both for controls and for the case samples.
  • Exclusion Criteria:
  • * Patients \< 18 years of age
  • * Patients who are not able to sign an informed consent
  • * Patients with suspected PDAC non confirmed at pathological report

About Irccs San Raffaele

IRCCS San Raffaele is a prestigious research hospital and clinical trial sponsor based in Milan, Italy, renowned for its commitment to advancing medical science through innovative research and high-quality patient care. As an Institute for Research and Healthcare, it specializes in a wide range of therapeutic areas, including oncology, neurology, and cardiology, and is dedicated to translating scientific discoveries into effective clinical practices. With a multidisciplinary team of experts and state-of-the-art facilities, IRCCS San Raffaele plays a pivotal role in conducting rigorous clinical trials that contribute to the development of novel treatments and improve patient outcomes globally.

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Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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