Influence of Different Prostheses on Postoperative Clinical Function in Total Knee Arthroplasty

Launched by THE AFFILIATED NANJING DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL · Sep 25, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how different types of knee implants, called prostheses, affect patients' knee function after total knee replacement surgery. Specifically, it compares two types of prostheses: one that keeps the knee's cruciate ligament (CR) and another that stabilizes the knee in a different way (PS). The goal is to understand which type of implant helps patients recover better and have improved movement after surgery.

To participate in the trial, individuals must be between 45 and 80 years old and have a body mass index (BMI) under 35. They should have been diagnosed with severe knee arthritis in both knees and need to have surgery on both knees at the same time. However, those who have had previous knee surgeries or have certain knee conditions may not be eligible. Participants can expect to undergo surgery with one of the two types of prostheses and will be monitored afterward to see how well they can move their knees and perform daily activities. This study is important as it aims to provide valuable insights that could help improve knee replacement outcomes for many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 45-80 years, any gender, BMI \< 35 kg/m2
• • 2. Initial diagnosis of bilateral knee OA (Kellgren-Lawrence classification grades 3 or 4). Patients who are to undergo simultaneous primary bilateral knee arthroplasty
• • 3. Inversion deformity ≤ 15°
• • 4. Posterior cruciate ligament integrity
• Exclusion Criteria:
• • 1. History of knee surgery (ligament, osteotomy, etc.)
• • 2. knee flexion\<90°.
• • 3. flexion contracture of one knee \> 10°
• • 4. Comorbidity with other diseases, such as peripheral neuropathy, malignant tumors, rheumatism, etc.
• • 5. Posterior cruciate ligament injury
• • 6. Those assessed to be intolerant of surgery