Efficacy of a Low FODMAP Diet in IBS Children and Impact on Urinary and Faecal Metabolome

Launched by UNIVERSITY OF BARI · Sep 27, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a low FODMAP diet can help children with irritable bowel syndrome (IBS), a condition that causes abdominal pain and changes in bowel habits. The low FODMAP diet focuses on reducing certain types of carbohydrates that can be hard for the body to digest, which may help relieve symptoms like bloating and discomfort. While this diet has shown promise in adults, there is limited research on its effects in children, which this study aims to address.

To participate in the trial, children aged 4 to 18 with a diagnosis of IBS and no other significant medical conditions may be eligible. Participants will go through different phases, starting with a period to assess their usual symptoms, followed by a two-week period on either the low or a standard diet. After a short break, they will switch diets for another two weeks. Throughout the study, researchers will monitor how each diet affects the children's symptoms and analyze their urine and stool samples to understand the impact on their gut health. Families interested in this trial should know that it is being conducted at the Pediatric Gastroenterology Unit at the University of Bari, and they are currently recruiting participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • a) age between 4 and 18 years; b) diagnosis of IBS according to Rome IV criteria; c) absence of other organic diseases; d) feeding via the oral route; e) ability to read and comprehend any employed questionnaires/scales; f) signed informed consent;
• Exclusion Criteria:
• • a) organic disease b)some other FGID (not IBS) or lactose intolerance c) having already followed an exclusion diet d)in case of pregnancy e)eating disorders f) prior surgery of the gastrointestinal tract g) neurodevelopmental disabilities