CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia
Launched by ZAGAZIG UNIVERSITY · Sep 29, 2024
Trial Information
Current as of July 21, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at two different ways to treat a painful condition called idiopathic trigeminal neuralgia (TN), which affects the face and can cause severe pain. The two methods being compared are CT-guided and fluoroscopy-guided trigeminal ganglion radiofrequency thermocoagulation (TG-RFT). The goal is to see which method provides better pain relief, requires fewer pain medications, and has fewer complications after the procedure.
To participate in the trial, you need to be at least 18 years old and have been experiencing facial pain for at least six months that hasn't improved with other treatments. Participants will undergo one of the two procedures and will be monitored for up to six months afterward to track their pain levels, medication use, and any side effects. If you’re interested in joining this study, it's important to know that there are certain health conditions that might exclude you from participating, such as having other specific medical issues or previous surgeries for TN.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age \>18 years
- • Idiopathic trigeminal neuralgia (TN) based on the International Headache Society criteria
- • Pain for at least six months and a NRS score greater than 6 despite medical treatment
- • Able to provide informed consent.
- • Agree to follow the study procedures and attend follow-up visits.
- Exclusion Criteria:
- • Vascular compression of the trigeminal nerve by MRI and MRI angiography and the presence of secondary causes such as multiple sclerosis
- • Trigeminal autonomic cephalalgias accompanied by autonomic symptoms
- • Dental or temporomandibular joint pathologies
- • Previous interventional procedures or surgery for TN
- • Coagulopathy or use of antiaggregants and anticoagulants
- • Cardiac pacemaker
- • Renal-hepatic insufficiency
- • Diagnosis of psychiatric illness
- • Malignancy
- • Injection site or systemic infection
- • Current participation in another clinical trial that could interfere with the outcomes of this study.
About Zagazig University
Zagazig University, a prominent educational and research institution located in Egypt, plays a pivotal role in advancing medical knowledge and promoting health innovations through its clinical trials. With a commitment to excellence in research, the university leverages its diverse expertise and state-of-the-art facilities to conduct rigorous clinical studies that aim to improve patient care and outcomes. By fostering collaboration among multidisciplinary teams, Zagazig University contributes significantly to the global medical community, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Zagazig, El Sharkia, Egypt
Patients applied
Trial Officials
Ahmed A Bessar, MD, PhD
Principal Investigator
Assistant Professor of Diagnostic and Interventional Radiology, Zagazig Uni.
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported