Clinical Findings and Albuminuria as Predictors of Acute Kidney Injury in Patients With Acute Heart Failure

Launched by HAGAR MAHMOUD HAMMAD · Sep 28, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to understand how well certain clinical signs and levels of protein in urine (called albuminuria) can predict acute kidney injury (AKI) in patients who are experiencing acute heart failure. Acute heart failure is a serious condition where the heart suddenly can't pump blood effectively. The study will help determine if these early tests can also give doctors important information about a patient’s risk of complications, including death, while they are in the hospital.

To participate in this trial, you need to be at least 18 years old and admitted to the Intensive Care Unit (ICU) with acute heart failure. Some patients will not be eligible, such as those under 18 or those who already have chronic kidney disease, which is a long-term condition affecting kidney function. If you join the study, you will undergo examinations and tests to measure your kidney function and protein levels in your urine, helping researchers learn more about managing heart failure effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients of 18 years and older who will be admitted to the ICU with acute heart failure (acute heart failure is defined according ESC guidelines 2021 which include Heart Failure with Reduced Ejection Fraction (HFrEF) EF \<40% . Mid-Range Ejection Fraction (HFmrEF)(41 -46 %) , Preserved Ejection Fraction (HFpEF) EF ≥ 50%.
• Exclusion Criteria:
• • patients under the age of 18.
• • Patients with known chronic kidney disease (CKD) before ICU admission (CKD is defined as the presence of kidney damage or an estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73 mt2, persisting for 3 months or more, and or albuminuria more than 3.5 mg/mmol (12)
• • severe UTI