Use of Sodium Bicarbonate As Prophylaxis for Kidney Damage in Patients with Heatstroke

Launched by HOSPITAL GENERAL DE MEXICALI · Sep 30, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring whether sodium bicarbonate (a common ingredient in baking soda) can help prevent kidney damage in patients who experience heatstroke, particularly those who have high levels of a muscle enzyme called CPK. The study is taking place at the General Hospital of Mexicali during the summer months and aims to see if giving sodium bicarbonate can reduce the risk of needing dialysis, a treatment for severe kidney failure.

To participate in this trial, individuals must be admitted to the hospital with heatstroke, which is defined as having a body temperature above 40 degrees Celsius and a CPK level greater than 1000 U/L. Participants will be those aged 65 to 74, and both men and women are welcome to join. Those who do not have a confirmed diagnosis of heatstroke or lack kidney function information at the time of admission will not be eligible. If you or a loved one meet these criteria, this trial may offer a potential way to protect kidney health during recovery from heat-related illnesses.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Admitted to the General Hospital of Mexicali with the diagnosis of heat stroke.
• • Meeting the operational definition (exposure to heat, body temperature at admission greater than 40 degrees Celsius).
• • CPK level greater than 1000 U/L.
• • Having informed consent from the patient or the legally responsible adult.
• Exclusion Criteria:
• • Exclusion of the heat stroke diagnosis during their evaluation.
• • Lack of serum creatinine levels at the time of admission to the protocol.