Severe Asthma Network Italy

Launched by SOCIETÀ ITALIANA DI ALLERGOLOGIA, ASMA E IMMUNOLOGIA CLINICA · Oct 1, 2024

Keywords

ClinConnect Summary

The Severe Asthma Network Italy trial is focused on understanding how severe asthma affects patients in real life. Researchers are collecting information from patients who have been diagnosed with severe asthma at specialized centers. This data will help evaluate how well patients are sticking to their treatments, how effectively the treatments are working, and how safe they are over the long term. By following these patients over time, the study aims to gather a clearer picture of severe asthma and improve future treatments.

If you or someone you know is over 12 years old and has been diagnosed with severe asthma, you might be eligible to participate in this study. To qualify, participants must be receiving specific asthma treatments, such as high doses of inhaled steroids or oral corticosteroids. Participants can expect to share their medical information and experiences, which will contribute to a better understanding of severe asthma and potentially lead to improved care for others with the condition. This study is currently recruiting, and it aims to provide valuable insights into managing severe asthma effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. signed informed consent and privacy disclaimer;
• • 2. age \> 12 years;
• 3. diagnosis of severe asthma according to the ERS/ATS criteria:
• 1. During treatment with:
• • High-dose ICS + at least one addistional controller (LABA, montelukast, or theophylline) or
• • Oral corticosteroids \>6 months/year
• 2. at least one of the following occurs or would occur if treatment would be reduced:
• • ACT \<20 or ACQ\>1.5
• • At least 2 exacerbations in the last 12 months
• • At least 1 exacerbation treated in hospital or requiring mechanical ventilation in the last 12 months
• • FEV1 \<80% (if FEV1/FVC below the lower limit of normal)
• • Exclusion Criteria have not been considered in order to have a realistic view of severe asthma in real life.