ClinConnect ClinConnect Logo
Search / Trial NCT06625645

Comparative Evaluation of Antimicrobial Efficacy, Clinical and Radiographic Success of Calcium Hydroxide, Chlorhexidine, and Modified Triple Antibiotic Paste in Different Combination Forms As Intracanal Medicaments Against Enterococcus Faecalis in Primary Teeth

Launched by MAHY ABDEL RAOUF ALY KAMAR · Oct 1, 2024

Trial Information

Current as of June 29, 2025

Not yet recruiting

Keywords

Necrotic Primary Teeth Apical Periodontitis Non Vital Primary Teeth Periapical Pathosis Of Primary Teeth Intracanal Medication Triple Antibiotic Paste Enterococcus Faecalis Microbiology Bacterial Reduction

ClinConnect Summary

This clinical trial is designed to compare the effectiveness of different treatments used inside decayed primary (baby) teeth that have become infected. Specifically, it looks at three types of medications: Calcium Hydroxide, Chlorhexidine, and Modified Triple Antibiotic Paste. The goal is to see which combination of these treatments works best to reduce harmful bacteria, particularly a type called Enterococcus faecalis, and to determine how well these treatments help the tooth heal over a year.

To be eligible for this study, children must have certain issues with their primary molars, such as severe decay leading to pulp necrosis (dead nerve tissue), and they must show signs of pain. However, children who have health problems that make them uncooperative, or who have teeth that are too damaged or already need to be removed, will not be included. Participants can expect to undergo a procedure called pulpectomy, where the infected pulp is removed and treated, and they will be followed up for one year to monitor the tooth's healing process. Remember, this trial is not yet recruiting participants, so more information will be available in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • • Primary molars necessitating pulpectomy diagnosed with deep dental caries with pulp necrosis, apical periodontitis and periapical pathosis or both.
  • Non-Vital pulps.
  • Negative response to hot or cold pulp tester (ethyl chloride spray ).
  • Decayed tooth with spontaneous unprovoked long dull aching pain showing signs of necrosis of the pulp
  • Exclusion Criteria:
  • Medically compromised and uncooperative children
  • Tooth indicated for extraction
  • Mobile teeth (Miller's Grade 2 or more)
  • teeth with more than two-thirds of root resorption
  • previous endodontic treatment

About Mahy Abdel Raouf Aly Kamar

Mahy Abdel Raouf Aly Kamar is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes through innovative trial design and rigorous scientific methodologies. With a focus on ethical practices and regulatory compliance, the organization collaborates with a diverse network of healthcare professionals and institutions to facilitate the development of new therapies. Leveraging extensive experience in clinical operations, Mahy Abdel Raouf Aly Kamar aims to drive meaningful contributions to the healthcare landscape, ensuring that each study is conducted with the highest standards of quality and integrity.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported