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Search / Trial NCT06625762

Nantes Bariatric Surgery Cohort

Launched by NANTES UNIVERSITY HOSPITAL · Oct 1, 2024

Trial Information

Current as of August 20, 2025

Not yet recruiting

Keywords

Obesity Bariatric Surgery Biological Aging Adipocyte Dysfunction Biological Rhythms

ClinConnect Summary

The Nantes Bariatric Surgery Cohort study is exploring how weight-loss surgery, known as bariatric surgery, might affect the biological age of individuals with obesity. Researchers want to understand if this type of surgery can lead to improvements in how fat cells function, changes in gut bacteria, and better biological rhythms, and if these changes are connected to aging. To answer these questions, the study will collect samples from participants before, during, and after their surgery.

To be eligible for this study, individuals must be over 18 years old and have a body mass index (BMI) of 35 or higher with health complications, or a BMI of 40 or higher, regardless of complications. Participants must also agree to join the study and be part of a social security program. However, individuals who are pregnant, nursing, or under legal guardianship cannot participate. The study is not yet recruiting, but it aims to provide valuable insights into how bariatric surgery could improve health outcomes for people dealing with obesity.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria :
  • Individuals selected for bariatric surgery (starting the BC pathway within the Nantes University Hospital bariatric unit). Inclusion criteria are those of the Bariatric Surgery program.
  • male or female, adult over 18 years of age
  • BMI ≥ 35 kg/m2 with complication(s) or ≥ 40 kg/m2 with or without complication (the list of eligible complications is referenced in HAS 2024 recommendations). In the event of a change in access to bariatric surgery, this threshold could be revised without any substantial change to the protocol.
  • having consented to their participation in the cohort
  • participant affiliated to or benefiting from a social security scheme
  • Exclusion Criteria :
  • Persons protected by law (guardianship or trusteeship) or deprived of their freedom,
  • Pregnant women (contraindication to CB) or nursing mothers.

About Nantes University Hospital

Nantes University Hospital, a leading academic medical institution in France, is dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge scientific exploration with patient care, fostering collaborations among multidisciplinary teams of healthcare professionals and researchers. With a strong emphasis on ethical standards and patient safety, Nantes University Hospital aims to contribute to the development of effective therapies and interventions that enhance patient outcomes and overall public health.

Locations

Nantes, Loire Atlantique, France

Patients applied

0 patients applied

Trial Officials

David JACOBI, PU-PH

Principal Investigator

Nantes University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported