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Search / Trial NCT06627686

Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury

Launched by BENHA UNIVERSITY · Oct 3, 2024

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at ways to predict whether patients with traumatic brain injuries can successfully stop using a breathing machine (called mechanical ventilation). The researchers will measure specific breathing strength indicators, such as how much air a patient can inhale and the pressure in their airways, to see if these measurements can help determine if a patient is ready to be taken off the ventilator.

To be eligible for this study, patients must be between 18 and 65 years old, have a closed traumatic brain injury, and have been on the ventilator for more than 24 hours. They also need to show signs that their breathing problems are improving and that their overall health is stable. Participants in the trial will undergo tests to measure their breathing strength and pressure, and the results may help improve the care of future patients in similar situations.

Gender

ALL

Eligibility criteria

  • Traumatic brain injury (closed type) patients who will be admitted to ICU and intubated and MV more than 24 hours will be included in this study.
  • Age from 18 to 65 years (male or female).
  • Fulfillment of Criteria of readiness for weaning off MV :
  • Resolution of the cause of respiratory insufficiency and MV. Stable hemodynamic profile

About Benha University

Benha University, a leading institution in Egypt, is dedicated to advancing medical research and innovation through rigorous clinical trials. With a strong emphasis on multidisciplinary collaboration, the university aims to enhance healthcare outcomes by exploring novel therapeutic approaches and interventions. Its state-of-the-art facilities and commitment to ethical research practices ensure that all trials are conducted with the highest standards of integrity and scientific rigor. Benha University actively contributes to the global medical community by fostering partnerships and disseminating findings that can improve patient care and inform public health policies.

Locations

Tanta, Mahala, Egypt

Patients applied

0 patients applied

Trial Officials

Ali Rashad, MBBCH

Principal Investigator

Benha University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported