Artemisia and Green Tea Extracts for Gastric Mucosal Health

Launched by PUSAN NATIONAL UNIVERSITY YANGSAN HOSPITAL · Oct 4, 2024

Keywords

ClinConnect Summary

Researchers will compare Artemisia and green tea extracts to placebo to evaluate their effectiveness in promoting gastric mucosal health.

Participants will:

* Take Artemisia and green tea extracts or a placebo daily for 8 weeks.
* Visit the clinic every 4 weeks for checkups and tests.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Rome IV-based functional dyspepsia-
• Exclusion Criteria:
• • Patients with gastrointestinal symptoms requiring immediate drug treatment.
• • Individuals with a history of hypersecretory gastric disorders like Zollinger-Ellison syndrome.
• • Individuals who received Helicobacter pylori eradication therapy within 4 weeks prior to the trial.
• • Individuals who have taken nonsteroidal anti-inflammatory drugs, steroids, antibiotics, aspirin, antithrombotic agents, or acid suppressants within the last month.
• • Individuals with a history of upper gastrointestinal surgery, stricture, bleeding, or procedures like esophageal dilation or mucosal resection within the last year.
• • Individuals with gastric ulcers (active or healing), duodenal ulcers (active or healing), reflux esophagitis (LA grade A or higher), or malignant tumors identified within the last 6 months through endoscopy.
• • Patients with uncontrolled hypertension (resting BP ≥160/100 mmHg).
• • Patients with uncontrolled diabetes (fasting glucose ≥160 mg/dL).
• • Individuals with creatinine levels ≥ 2 times the upper limit of normal at the research institution.
• • Individuals with aspartate aminotransferase or alanine aminotransferase levels ≥ 2 times the upper limit of normal at the research institution.
• • Alcohol abusers.
• • Individuals taking medications for psychiatric disorders (except those taking intermittent medication for sleep disorders).
• • Pregnant or breastfeeding women or those planning to become pregnant during the clinical trial period.
• • Individuals with allergies to any components of the study foods.
• • Individuals who participated in or plan to participate in another drug clinical trial within the last month.
• • Individuals deemed unsuitable for the study by the investigator for other reasons.