Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

Launched by UNIVERSITY OF MICHIGAN · Oct 4, 2024

Keywords

ClinConnect Summary

This clinical trial, called "Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing," aims to help older adults who may be taking too much thyroid hormone medication. The study is testing a new approach, known as D-THIO, which focuses on safely reducing or stopping thyroid hormone treatment for those who don't need it. The goal is to prevent potential harm from unnecessary medication and set a standard for managing other similar health conditions in the future.

To be part of this study, participants must be 65 years or older, currently taking thyroid hormone, and have a specific test result showing they might be getting too much. They also need to be able to speak English and not have any issues with memory or thinking. Those with certain medical conditions, such as thyroid cancer or recent hospital stays, won’t be included. Participants will work with healthcare providers who specialize in this area, and those providers will help guide them through the process of safely adjusting their medications. Overall, this study aims to improve the health and well-being of older adults by ensuring they receive appropriate medication management.

Gender

ALL

Eligibility criteria

• Patient Eligibility:
• Inclusion Criteria:
• • 1. age 65 years and older
• • 2. on thyroid hormone therapy and have a serum Thyroid-stimulating hormone (TSH) \<0.5 mIU/L or are on thyroid hormone therapy for an inappropriate indication
• • 3. English speaking
• • 4. without cognitive impairment
• Exclusion Criteria:
• • 1) Patients with a diagnosis of thyroid cancer, secondary hypothyroidism, history of total thyroidectomy or hospitalization in the past 3 months will be excluded.
• Provider eligibility:
• • Inclusion: Primary care physicians, endocrinologists, geriatricians, and Advanced Practice Providers (APPs) who practice at University of Michigan, Henry Ford Health System or University of California San Fransico (UCSF) and who prescribe thyroid hormone for eligible patients identified above will be eligible for study participation.
• • Exclusion: Providers who don't prescribe thyroid hormone.