Investigate the Efficacy of Using NMN to Improve Embryo Development Capacity.

Launched by SUNKAKY MEDICAL COOPERATION · Oct 3, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how a supplement called NMN might help improve the development of embryos and increase the chances of success for women who have had repeated failures with in vitro fertilization (IVF). The study is open to women aged 32 to 42 who have experienced at least one failed embryo implantation and have had issues with embryo quality. Participants will need to meet certain health criteria and should not have specific medical conditions that could affect their ability to take part.

If you join this study, you can expect to receive NMN supplements as part of the trial. Researchers are interested in seeing if this supplement can enhance embryo development, which could lead to better outcomes in IVF treatments. It's important to note that there are strict eligibility requirements, so not everyone will qualify. If you think you might be eligible and are interested in participating, be sure to discuss it with your healthcare provider to understand more about the benefits and risks involved.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Agree to participate in the study
• • 32-42 years old
• • Having at least one previous embryo implantation failure
• • History of low Embryo quality at day3 or day5 (according to Veeck's and Gardner's Criteria)
• • No major uterine or ovarian abnormalities
• • BMI level 18-25kg/m2
• Exclusion Criteria:
• • Ovarian endometriosis with Chocolate cysts (AFS type 3 and 4)
• • Patients who have taken different supplements such as coenzyme Q10, vitamin E, carnitine,niacin, nicotinamide, or other vitamin B3-related etc. within the previous month
• • Any medical contraindication of oocyte retrieval or subsequent procedures
• • Couples where the husband presents with severe sperm abnormalities
• • Couples where the husband presents \<5 million/mL motile sperm
• • Uterine structural anomalies
• • Polycystic ovaries
• • Premature ovarian failure
• • Individuals who need regular medication to treat chronic diseases such as diabetes, hypertension, gout, hyperuricemia, etc.
• • Individuals who need drug treatment for any mental illness such as epilepsy and depression.
• • Individuals who suffer from infectious diseases such as hepatitis B, active tuberculosis, AIDS, etc.
• • Cancer patients or receiving chemo/radiotherapy treatment within the past 3 years.