FIT Exercise in 30d of ULLS-induced Muscle Disuse

Launched by LANCE BOLLINGER · Oct 5, 2024

Keywords

ClinConnect Summary

This clinical trial is exploring how a specific type of exercise called flywheel-based inertial training (FIT) can help people who have experienced muscle weakness and loss of strength due to inactivity. The study focuses on using a combination of high-intensity workouts and exercises that adapt to how fast a person is moving. Researchers want to see if this training can improve muscle strength, aerobic fitness (how well your body uses oxygen during exercise), and balance in individuals who have had reduced physical activity.

To participate in this trial, you need to have been exercising regularly for at least a year, including both aerobic exercises (like running or cycling) and strength training (like lifting weights). You should also have at least a bachelor’s degree. However, people with certain health issues, recent injuries, or specific body measurements may not be eligible to join. If you decide to participate, you can expect to engage in a structured exercise program designed to help improve your physical condition over the course of 30 days, while being closely monitored by the research team. This study aims to offer insights into effective ways to combat muscle loss and weakness during periods of inactivity.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Regularly engaging in aerobic exercise (\> 150min/wk) and resistance exercise (\>1 time per week) for the past 12 months
• • Education greater than or equal to bachelor's degree (any field)
• Exclusion Criteria:
• • Waist circumference \< 55cm or \> 90cm (F) and \< 75cm or \> 100cm (M)
• • Body mass index \< 18.5 or \> 29.9
• • Shoe size \< 25 or \>29cm.
• • Not regularly engaging in exercise for previous 12 months
• • Tobacco use within previous 6 months
• • Blood clotting disorder
• • Heart arrhythmia
• • Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
• • Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
• • Pregnancy (within previous 6 months)
• • Oral contraceptive use (within previous three months)
• • High resting blood pressure (\>140 systolic and/or \> 90 diastolic)
• • Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
• • Low back or leg injury in previous 6 months
• • Currently taking medication to assist with sleep
• • Muscle, bone, or joint injury that limits physical activity within previous 6 months
• • Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)