Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
Launched by CAIRO UNIVERSITY · Oct 6, 2024
Trial Information
Current as of July 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how different methods of reconstructing the anterior cruciate ligament (ACL) in the knee affect the stability of the ankle joint. Specifically, it compares the use of a tendon from the peroneus longus (a muscle in the leg) to a common alternative graft. The researchers are interested in understanding how these procedures might impact balance and stability in the ankle, especially since the ankle is crucial for maintaining good posture and movement.
To participate in this trial, individuals should be between 15 and 45 years old and have a specific type of ACL tear without other major knee injuries. Participants need to have healthy ankles and no prior ankle injuries or surgeries. If eligible, participants can expect to undergo ACL reconstruction using one of the two graft methods and will be monitored for their ankle stability and balance throughout the study. This research is important as it aims to improve outcomes for patients recovering from ACL injuries while ensuring their ankle function remains strong.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age ranging between 15- 45 years
- • Having unilateral isolated ACL tear with no concomitant tear of other ligaments of the knee
- • Having no evidence of meniscal repair
- • Having bilateral healthy ankle before surgery.
- • Exclusion Criteria
- • Pre-existing ankle injury or ankle instability
- • Associated ligament injury, chondral damage, meniscal injury, fracture around the knee, and presence of pathologic condition in the lower extremity or an abnormal contralateral knee joint.
- • Visible mal-alignments in the lower extremities.
- • Previous surgery to the affected knee.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Trial Officials
Lamyaa Kotb Elsayad, PHd
Study Director
Cairo University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported